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SUMOylation of the GTPase Rac1 is required for optimal cell migration
The Rho-like GTPase Rac1 induces cytoskeletal rearrangements required for cell migration. Rac activity is regulated through a number of mechanisms, including control of nucleotide exchange and hydrolysis, regulation of subcellular localization, or modulation of protein expression levels1-3. Here, we...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2992316/ https://ncbi.nlm.nih.gov/pubmed/20935639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2112 |
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