Tiam1-Rac Signaling Counteracts Eg5 during Bipolar Spindle Assembly to Facilitate Chromosome Congression

Centrosome separation, critical for bipolar spindle formation and subsequent chromosome segregation during mitosis, occurs via distinct prophase and prometaphase pathways [1–3]. Kinesin-5 (Eg5), a microtubule (MT) motor, pushes centrosomes apart during bipolar spindle assembly [4]; its suppression r...

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Bibliografski detalji
Glavni autori: Woodcock, Simon A., Rushton, Helen J., Castañeda-Saucedo, Eduardo, Myant, Kevin, White, Gavin R.M., Blyth, Karen, Sansom, Owen J., Malliri, Angeliki
Format: Artigo
Jezik:Inglês
Izdano: Cell Press 2010
Teme:
Report
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989435/
https://ncbi.nlm.nih.gov/pubmed/20346677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2010.02.033
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