Tiam1-Rac Signaling Counteracts Eg5 during Bipolar Spindle Assembly to Facilitate Chromosome Congression

Centrosome separation, critical for bipolar spindle formation and subsequent chromosome segregation during mitosis, occurs via distinct prophase and prometaphase pathways [1–3]. Kinesin-5 (Eg5), a microtubule (MT) motor, pushes centrosomes apart during bipolar spindle assembly [4]; its suppression r...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Woodcock, Simon A., Rushton, Helen J., Castañeda-Saucedo, Eduardo, Myant, Kevin, White, Gavin R.M., Blyth, Karen, Sansom, Owen J., Malliri, Angeliki
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cell Press 2010
Pynciau:
Report
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989435/
https://ncbi.nlm.nih.gov/pubmed/20346677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2010.02.033
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