The Rac activator STEF (Tiam2) regulates cell migration by microtubule-mediated focal adhesion disassembly

Focal adhesion (FA) disassembly required for optimal cell migration is mediated by microtubules (MTs); targeting of FAs by MTs coincides with their disassembly. Regrowth of MTs, induced by removal of the MT destabilizer nocodazole, activates the Rho-like GTPase Rac, concomitant with FA disassembly....

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Rooney, Claire, White, Gavin, Nazgiewicz, Alicja, Woodcock, Simon A, Anderson, Kurt I, Ballestrem, Christoph, Malliri, Angeliki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2010
Soggetti:
Scientific Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854589/
https://ncbi.nlm.nih.gov/pubmed/20224579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2010.10
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi