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The Rac activator STEF (Tiam2) regulates cell migration by microtubule-mediated focal adhesion disassembly
Focal adhesion (FA) disassembly required for optimal cell migration is mediated by microtubules (MTs); targeting of FAs by MTs coincides with their disassembly. Regrowth of MTs, induced by removal of the MT destabilizer nocodazole, activates the Rho-like GTPase Rac, concomitant with FA disassembly....
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2854589/ https://ncbi.nlm.nih.gov/pubmed/20224579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2010.10 |
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