Polyamine-dependent activation of Rac1 is stimulated by focal adhesion-mediated Tiam1 activation

Integrin receptors cluster on the cell surface and bind to extra cellular matrix (ECM) proteins triggering the formation of focal contacts and the activation of various signal transduction pathways that affect the morphology, motility, gene expression and survival of adherent cells. Polyamine deplet...

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Bibliographic Details
Main Authors: Elias, Bertha C, Bhattacharya, Sujoy, Ray, Ramesh M, Johnson, Leonard R
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2010
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958619/
https://ncbi.nlm.nih.gov/pubmed/20448461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cam.4.3.12043
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