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Polyamine-dependent activation of Rac1 is stimulated by focal adhesion-mediated Tiam1 activation
Integrin receptors cluster on the cell surface and bind to extra cellular matrix (ECM) proteins triggering the formation of focal contacts and the activation of various signal transduction pathways that affect the morphology, motility, gene expression and survival of adherent cells. Polyamine deplet...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Landes Bioscience
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2958619/ https://ncbi.nlm.nih.gov/pubmed/20448461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cam.4.3.12043 |
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