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Activation of Dbl restores migration in polyamine-depleted intestinal epithelial cells via Rho-GTPases
Integrin binding to the extracellular matrix (ECM) activated Rho GTPases, Src, and focal adhesion kinase in intestinal epithelial cells (IEC)-6. Polyamine depletion inhibited activities of Rac1, RhoA, and Cdc42 and thereby migration. However, constitutively active (CA) Rac1 expression abolished the...
Tallennettuna:
| Päätekijät: | , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Physiological Society
2011
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3119111/ https://ncbi.nlm.nih.gov/pubmed/21372162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00409.2010 |
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