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The RAC1 activator Tiam1 regulates centriole duplication through controlling PLK4 levels
Centriole duplication is tightly controlled to maintain correct centriole number through the cell cycle. Key to this is the regulated degradation of PLK4, the master regulator of centriole duplication. Here, we show that the Rac1 guanine nucleotide exchange factor (GEF) Tiam1 localises to centrosome...
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| Pubblicato in: | J Cell Sci |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Company of Biologists Ltd
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8075378/ https://ncbi.nlm.nih.gov/pubmed/33758078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.252502 |
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