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The interaction between CASK and the tumour suppressor Dlg1 regulates mitotic spindle orientation in mammalian epithelia

Oriented cell divisions are important for the formation of normal epithelial structures. Dlg1, a tumour suppressor, is required for mitotic spindle orientation in Drosophila epithelia and chick neuroepithelia, but how Dlg1 is localised to the membrane and its importance in mammalian epithelia are un...

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Библиографические подробности
Опубликовано в: :J Cell Sci
Главные авторы: Porter, Andrew P., White, Gavin R. M., Mack, Natalie A., Malliri, Angeliki
Формат: Artigo
Язык:Inglês
Опубликовано: The Company of Biologists Ltd 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6679578/
https://ncbi.nlm.nih.gov/pubmed/31289196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.230086
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