GEFs: Dual regulation of Rac1 signaling

von Marei, Hadir, Malliri, Angeliki
Veröffentlicht in Small GTPases (2016)

Rac1 in human diseases: The therapeutic potential of targeting Rac1 signaling regulatory mechanisms

von Marei, Hadir, Malliri, Angeliki
Veröffentlicht in Small GTPases (2016)

Centrosome separation; a careful balancing act

von Whalley, Helen J, Malliri, Angeliki
Veröffentlicht in Cell Cycle (2015)

Deregulation of Rho GTPases in cancer

von Porter, Andrew P., Papaioannou, Alexandra, Malliri, Angeliki
Veröffentlicht in Small GTPases (2016)

Proteomic analysis of Rac1 signaling regulation by guanine nucleotide exchange factors

von Marei, Hadir, Carpy, Alejandro, Macek, Boris, Malliri, Angeliki
Veröffentlicht in Cell Cycle (2016)

The diverse roles of Rac signaling in tumorigenesis

von Mack, Natalie A, Whalley, Helen J, Castillo-Lluva, Sonia, Malliri, Angeliki
Veröffentlicht 2011

The interaction between CASK and the tumour suppressor Dlg1 regulates mitotic spindle orientation in mammalian epithelia

von Porter, Andrew P., White, Gavin R. M., Mack, Natalie A., Malliri, Angeliki
Veröffentlicht in J Cell Sci (2019)

The Rac activator STEF (Tiam2) regulates cell migration by microtubule-mediated focal adhesion disassembly

von Rooney, Claire, White, Gavin, Nazgiewicz, Alicja, Woodcock, Simon A, Anderson, Kurt I, Ballestrem, Christoph, Malliri, Angeliki
Veröffentlicht 2010

Differential Rac1 signalling by guanine nucleotide exchange factors implicates FLII in regulating Rac1-driven cell migration

von Marei, Hadir, Carpy, Alejandro, Woroniuk, Anna, Vennin, Claire, White, Gavin, Timpson, Paul, Macek, Boris, Malliri, Angeliki
Veröffentlicht in Nat Commun (2016)

Cdk1 phosphorylates the Rac activator Tiam1 to activate centrosomal Pak and promote mitotic spindle formation

von Whalley, Helen J., Porter, Andrew P., Diamantopoulou, Zoi, White, Gavin R. M., Castañeda-Saucedo, Eduardo, Malliri, Angeliki
Veröffentlicht in Nat Commun (2015)

The RAC1 activator Tiam1 regulates centriole duplication through controlling PLK4 levels

von Porter, Andrew P., Reed, Hannah, White, Gavin R. M., Ogg, Erinn-Lee, Whalley, Helen J., Malliri, Angeliki
Veröffentlicht in J Cell Sci (2021)

The Transcription Factor AP-1 Is Required for EGF-induced Activation of Rho-like GTPases, Cytoskeletal Rearrangements, Motility, and In Vitro Invasion of A431 Cells

von Malliri, Angeliki, Symons, Marc, Hennigan, Robert F., Hurlstone, Adam F.L., Lamb, Richard F., Wheeler, Tricia, Ozanne, Bradford W.
Veröffentlicht 1998

SUMOylation of the GTPase Rac1 is required for optimal cell migration

von Castillo-Lluva, Sonia, Tatham, Michael H., Jones, Richard C., Jaffray, Ellis G., Edmondson, Ricky D., Hay, Ronald T., Malliri, Angeliki
Veröffentlicht 2010

Tiam1-Rac Signaling Counteracts Eg5 during Bipolar Spindle Assembly to Facilitate Chromosome Congression

von Woodcock, Simon A., Rushton, Helen J., Castañeda-Saucedo, Eduardo, Myant, Kevin, White, Gavin R.M., Blyth, Karen, Sansom, Owen J., Malliri, Angeliki
Veröffentlicht 2010

HUWE1 Ubiquitylates and Degrades the RAC Activator TIAM1 Promoting Cell-Cell Adhesion Disassembly, Migration, and Invasion

von Vaughan, Lynsey, Tan, Chong-Teik, Chapman, Anna, Nonaka, Daisuke, Mack, Natalie A., Smith, Duncan, Booton, Richard, Hurlstone, Adam F.L., Malliri, Angeliki
Veröffentlicht in Cell Rep (2014)

β2-syntrophin and Par-3 promote an apicobasal Rac activity gradient at cell-cell junctions by differentially regulating Tiam1 activity

von Mack, Natalie A., Porter, Andrew P., Whalley, Helen J., Schwarz, Juliane P., Jones, Richard C., Syed, Azharuddin Sajid, Bjartell, Anders, Anderson, Kurt I., Malliri, Angeliki
Veröffentlicht 2012

STEF/TIAM2-mediated Rac1 activity at the nuclear envelope regulates the perinuclear actin cap

von Woroniuk, Anna, Porter, Andrew, White, Gavin, Newman, Daniel T., Diamantopoulou, Zoi, Waring, Thomas, Rooney, Claire, Strathdee, Douglas, Marston, Daniel J., Hahn, Klaus M., Sansom, Owen J., Zech, Tobias, Malliri, Angeliki
Veröffentlicht in Nat Commun (2018)

Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes

von Daugaard, Mads, Nitsch, Roberto, Razaghi, Babak, McDonald, Lindsay, Jarrar, Ameer, Torrino, Stéphanie, Castillo-Lluva, Sonia, Rotblat, Barak, Li, Liheng, Malliri, Angeliki, Lemichez, Emmanuel, Mettouchi, Amel, Berman, Jason N., Penninger, Josef M., Sorensen, Poul H.
Veröffentlicht 2013

TIAM1 Antagonizes TAZ/YAP Both in the Destruction Complex in the Cytoplasm and in the Nucleus to Inhibit Invasion of Intestinal Epithelial Cells

von Diamantopoulou, Zoi, White, Gavin, Fadlullah, Muhammad Z.H., Dreger, Marcel, Pickering, Karen, Maltas, Joe, Ashton, Garry, MacLeod, Ruth, Baillie, George S., Kouskoff, Valerie, Lacaud, Georges, Murray, Graeme I., Sansom, Owen J., Hurlstone, Adam F.L., Malliri, Angeliki
Veröffentlicht in Cancer Cell (2017)

Ultraviolet light-induced collagen degradation inhibits melanoma invasion

von Budden, Timothy, Gaudy-Marqueste, Caroline, Porter, Andrew, Kay, Emily, Gurung, Shilpa, Earnshaw, Charles H., Roeck, Katharina, Craig, Sarah, Traves, Víctor, Krutmann, Jean, Muller, Patricia, Motta, Luisa, Zanivan, Sara, Malliri, Angeliki, Furney, Simon J., Nagore, Eduardo, Virós, Amaya
Veröffentlicht in Nat Commun (2021)