Molecular Targets in Precision Chemoprevention of Colorectal Cancer: An Update from Pre-Clinical to Clinical Trials

Por Yarla, Nagendra S., Madka, Venkateshwar, Pathuri, Gopal, Rao, Chinthalapally V.
Publicado no Int J Mol Sci (2020)

Clinically Relevant Anti-Inflammatory Agents for Chemoprevention of Colorectal Cancer: New Perspectives

Por Mohammed, Altaf, Yarla, Nagendra Sastry, Madka, Venkateshwar, Rao, Chinthalapally V.
Publicado no Int J Mol Sci (2018)

Prevention and Treatment of Cancers by Immune Modulating Nutrients

Por Janakiram, Naveena B., Mohammed, Altaf, Madka, Venkateshwar, Kumar, Gaurav, Rao, Chinthalapally V.
Publicado no Mol Nutr Food Res (2016)

p53-stabilizing Agent CP-31398 Prevents Growth and Invasion of Urothelial Cancer of the Bladder in Transgenic UPII-SV40T Mice

Por Madka, Venkateshwar, Zhang, Yuting, Li, Qian, Mohammed, Altaf, Sindhwani, Puneet, Lightfoot, Stan, Wu, Xue-Re, Kopelovich, Levy, Rao, Chinthalapally V
Publicado em 2013

Evaluation of (99m)Tc-Probestin SPECT As a Novel Technique for Noninvasive Imaging of Kidney Aminopeptidase N Expression

Por Pathuri, Gopal, Madka, Venkateshwar, Hedrick, Andria F., Lightfoot, Stanley A., Awasthi, Vibhudutta, Cowley, Benjamin D., Rao, Chinthalapally V., Gali, Hariprasad
Publicado em 2014

Bisphosphonates Zometa and Fosamax Synergize with Metformin to Prevent AOM-induced Colon Cancer in F344 Rat Model

Por Madka, Venkateshwar, Kumar, Gaurav, Pathuri, Gopal, Zhang, Yuting, Lightfoot, Stanley, Asch, Adam S, Mohammed, Altaf, Steele, Vernon E., Rao, Chinthalapally V.
Publicado no Cancer Prev Res (Phila) (2019)

EGFR inhibitor gefitinib prevents progression of pancreatic lesions to carcinoma in a conditional LSL-Kras(G12D/+) transgenic mice model

Por Mohammed, Altaf, Janakiram, Naveena B, Li, Qian, Madka, Venkateshwar, Ely, Misty, Lightfoot, Stan, Crawford, Howard, Steele, Vernon E., Rao, Chinthalapally V.
Publicado em 2010

TP53 modulating agent, CP-31398 enhances antitumor effects of ODC inhibitor in mouse model of urinary bladder transitional cell carcinoma

Por Madka, Venkateshwar, Mohammed, Altaf, Li, Qian, Zhang, Yuting, Kumar, Gaurav, Lightfoot, Stan, Wu, Xueru, Steele, Vernon, Kopelovich, Levy, Rao, Chinthalapally V
Publicado no Am J Cancer Res (2015)

Simultaneous targeting of 5-LOX-COX and EGFR blocks progression of pancreatic ductal adenocarcinoma

Por Rao, Chinthalapally V., Janakiram, Naveena B., Madka, Venkateshwar, Devarkonda, Vishal, Brewer, Misty, Biddick, Laura, Lightfoot, Stan, Steele, Vernon E., Mohammed, Altaf
Publicado no Oncotarget (2015)

Targeting CCK2R for pancreatic cancer chemoprevention

Por Mohammed, Altaf, Janakiram, Naveena B, Suen, Chen, Stratton, Nicole, Lightfoot, Stanley, Singh, Anil, Pathuri, Gopal, Ritchie, Rebekah, Madka, Venkateshwar, Rao, Chinthalapally V
Publicado no Mol Carcinog (2019)

Discovery and Development of a Novel mPGES-1/5-LOX Dual Inhibitor LFA-9 for Prevention and Treatment of Chronic Inflammatory Diseases

Por Yarla, Nagendra Sastri, Pathuri, Gopal, Gali, Hariprasad, Terzyan, Simon, Panneerselvam, Janani, Chandrakesan, Parthasarathy, Scotti, Marcus Tullius, Houchen, Courtney, Madka, Venkateshwar, Rao, Chinthalapally V
Publicado no J Inflamm Res (2020)

Early and delayed intervention with Rapamycin prevents NNK-induced lung adenocarcinoma in A/J mice

Por PATLOLLA, JAGAN M.R., KOPELOVICH, LEVY, QIAN, LI, ZHANG, YUTING, KUMAR, GAURAV, MADKA, VENKATESHWAR, MOHAMMED, ALTAF, BIDDICK, LAURA, SADEGHI, MICHAEL, LIGHTFOOT, STAN, RAO, CHINTHALAPALLY V.
Publicado no Oncol Rep (2015)

Chemoprevention of urothelial cell carcinoma growth and invasion by the dual COX-LOX inhibitor licofelone in UPII-SV40T transgenic mice

Por Madka, Venkateshwar, Mohammed, Altaf, Li, Qian, Zhang, Yuting, Patlolla, Jagan M.R., Biddick, Laura, Lightfoot, Stan, Wu, Xue-Ru, Steele, Vernon, Kopelovich, Levy, Rao, Chinthalapally V.
Publicado no Cancer Prev Res (Phila) (2014)

Eflornithine (DFMO) Prevents Progression of Pancreatic Cancer by Modulating Ornithine Decarboxylase Signaling

Por Mohammed, Altaf, Janakiram, Naveena B., Madka, Venkateshwar, Ritchie, Rebekah L., Brewer, Misty, Biddick, Laura, Patlolla, Jagan Mohan R., Sadeghi, Michael, Lightfoot, Stan, Steele, Vernon E., Rao, Chinthalapally V.
Publicado no Cancer Prev Res (Phila) (2014)

Targeting mTOR and p53 signaling inhibits muscle invasive bladder cancer in vivo

Por Madka, Venkateshwar, Mohammed, Altaf, Li, Qian, Zhang, Yuting, Biddick, Laura, Patlolla, Jagan M.R., Lightfoot, Stan, Towner, Rheal A., Wu, Xue-Ru, Steele, Vernon E., Kopelovich, Levy, Rao, Chinthalapally V.
Publicado no Cancer Prev Res (Phila) (2015)

Simultaneous targeting of 5-LOX-COX and ODC block NNK-induced lung adenoma progression to adenocarcinoma in A/J mice

Por Kumar, Gaurav, Patlolla, Jagan Mohan R, Madka, Venkateshwar, Mohammed, Altaf, Li, Qian, Zhang, Yuting, Biddick, Laura, Singh, Anil, Gillaspy, Allison, Lightfoot, Stanley, Steele, Vernon E, Kopelovich, Levy, Rao, Chinthalapally V
Publicado no Am J Cancer Res (2016)

Development of a dietary formulation of the SHetA2 chemoprevention drug for mice

Por Benbrook, Doris M., Janakiram, Naveena B., Chandra, Vishal, Pathuri, Gopal, Madka, Venkateshwar, Stratton, Nicole C., Masamha, Chioniso P., Farnsworth, Cassadie N., Garcia-Contreras, Lucila, Hatipoglu, Manolya Kukut, Lighfoot, Stan, Rao, Chinthalapally V.
Publicado no Invest New Drugs (2017)

Lack of chemopreventive effects of P2X7R inhibitors against pancreatic cancer

Por Mohammed, Altaf, Janakiram, Naveena B., Madka, Venkateshwar, Pathuri, Gopal, Li, Qian, Ritchie, Rebekah, Biddick, Laura, Kutche, Hannah, Zhang, Yuting, Singh, Anil, Gali, Hariprasad, Lightfoot, Stan, Steele, Vernon E., Suen, Chen S., Rao, Chinthalapally V.
Publicado no Oncotarget (2017)

Intermittent dosing regimens of aspirin and naproxen inhibit azoxymethane-induced rat colon adenoma progression to adenocarcinoma and invasive carcinoma

Por Mohammed, Altaf, Janakiram, Naveena B., Madka, Venkateshwar, Zhang, Yuting, Singh, Anil, Biddick, Laura, Li, Qian, Lightfoot, Stanley, Steele, Vernon E., Lubet, Ronald A., Suen, Chen S., Miller, Mark Steven, Sei, Shizuko, Rao, Chinthalapally V.
Publicado no Cancer Prev Res (Phila) (2019)

Targeting pancreatitis blocks tumor-initiating stem cells and pancreatic cancer progression

Por Mohammed, Altaf, Janakiram, Naveena B., Madka, Venkateshwar, Brewer, Misty, Ritchie, Rebekah L., Lightfoot, Stan, Kumar, Gaurav, Sadeghi, Michael, Patlolla, Jagan Mohan R., Yamada, Hiroshi Y., Cruz-Monserrate, Zobeida, May, Randal, Houchen, Courtney W., Steele, Vernon E., Rao, Chinthalapally V.
Publicado no Oncotarget (2015)