Chemoprevention of urothelial cell carcinoma growth and invasion by the dual COX-LOX inhibitor licofelone in UPII-SV40T transgenic mice

Epidemiological and clinical data suggest that use of anti-inflammatory agents is associated with reduced risk for bladder cancer. We determined the chemopreventive efficacy of licofelone, a dual cyclooxygenase (COX)-lipoxygenase (LOX) inhibitor, in a transgenic UPII-SV40T mouse model of urothelial...

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Veröffentlicht in:Cancer Prev Res (Phila)
Hauptverfasser: Madka, Venkateshwar, Mohammed, Altaf, Li, Qian, Zhang, Yuting, Patlolla, Jagan M.R., Biddick, Laura, Lightfoot, Stan, Wu, Xue-Ru, Steele, Vernon, Kopelovich, Levy, Rao, Chinthalapally V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310686/
https://ncbi.nlm.nih.gov/pubmed/24795386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-14-0087
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