p53-stabilizing Agent CP-31398 Prevents Growth and Invasion of Urothelial Cancer of the Bladder in Transgenic UPII-SV40T Mice

The high prevalence of bladder cancer and its recurrence make it an important target for chemoprevention. About half of invasive urothelial tumors have mutations in p53. We determined the chemopreventive efficacy of a p53-stabilizing agent, CP-31398, in a transgenic UPII-SV40T mouse model of bladder...

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Detalhes bibliográficos
Main Authors: Madka, Venkateshwar, Zhang, Yuting, Li, Qian, Mohammed, Altaf, Sindhwani, Puneet, Lightfoot, Stan, Wu, Xue-Re, Kopelovich, Levy, Rao, Chinthalapally V
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3730047/
https://ncbi.nlm.nih.gov/pubmed/23908596
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