Discovery and Development of a Novel mPGES-1/5-LOX Dual Inhibitor LFA-9 for Prevention and Treatment of Chronic Inflammatory Diseases

BACKGROUND: Non-steroidal anti-inflammatory drugs, cyclooxygenase (COX)-2 selective inhibitors, have been explored for prevention and treatment of several inflammatory chronic conditions including arthritis, and cancer. However, the long-term use of these drugs is associated with gastrointestinal, r...

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Bibliografski detalji
Izdano u:J Inflamm Res
Glavni autori: Yarla, Nagendra Sastri, Pathuri, Gopal, Gali, Hariprasad, Terzyan, Simon, Panneerselvam, Janani, Chandrakesan, Parthasarathy, Scotti, Marcus Tullius, Houchen, Courtney, Madka, Venkateshwar, Rao, Chinthalapally V
Format: Artigo
Jezik:Inglês
Izdano: Dove 2020
Teme:
Original Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7781011/
https://ncbi.nlm.nih.gov/pubmed/33408499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JIR.S286110
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