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Bisphosphonates Zometa and Fosamax Synergize with Metformin to Prevent AOM-induced Colon Cancer in F344 Rat Model

Recent observational studies suggest that bisphosphonates (BPs) and anti-diabetes drugs are associated with colorectal cancer (CRC) risk reduction. Hence, we evaluated the CRC preventive effects of BPs (Zometa; Zom; and Fosamax; Fos), individually and when combined with metformin (Met), in azoxymeth...

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Detalhes bibliográficos
Publicado no:Cancer Prev Res (Phila)
Main Authors: Madka, Venkateshwar, Kumar, Gaurav, Pathuri, Gopal, Zhang, Yuting, Lightfoot, Stanley, Asch, Adam S, Mohammed, Altaf, Steele, Vernon E., Rao, Chinthalapally V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007371/
https://ncbi.nlm.nih.gov/pubmed/31699708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-19-0265
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