Eflornithine (DFMO) Prevents Progression of Pancreatic Cancer by Modulating Ornithine Decarboxylase Signaling

Ornithine decarboxylase (ODC) is the key rate limiting enzyme in the polyamine synthesis pathway and it is overexpressed in a variety of cancers. We found that polyamine synthesis and modulation of ODC signaling occurs at early stages of pancreatic precursor lesions and increases as the tumor progre...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cancer Prev Res (Phila)
Main Authors: Mohammed, Altaf, Janakiram, Naveena B., Madka, Venkateshwar, Ritchie, Rebekah L., Brewer, Misty, Biddick, Laura, Patlolla, Jagan Mohan R., Sadeghi, Michael, Lightfoot, Stan, Steele, Vernon E., Rao, Chinthalapally V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310684/
https://ncbi.nlm.nih.gov/pubmed/25248858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-14-0176
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados