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Antidiabetic Drug Metformin Prevents Progression of Pancreatic Cancer by Targeting in Part Cancer Stem Cells and mTOR Signaling

Epidemiologic studies have shown that diabetes mellitus is associated positively with increased risk of pancreatic ductal adenocarcinoma (PDAC), and recent meta-analysis studies showed that metformin, reduces the risk of pancreatic cancer (PC). We tested the effects of metformin on pancreatic intrae...

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Detalhes bibliográficos
Main Authors: Mohammed, Altaf, Janakiram, Naveena B, Brewer, Misty, Ritchie, Rebekah L, Marya, Anuj, Lightfoot, Stan, Steele, Vernon E, Rao, Chinthalapally V
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890699/
https://ncbi.nlm.nih.gov/pubmed/24466367
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