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Antidiabetic Drug Metformin Prevents Progression of Pancreatic Cancer by Targeting in Part Cancer Stem Cells and mTOR Signaling

Epidemiologic studies have shown that diabetes mellitus is associated positively with increased risk of pancreatic ductal adenocarcinoma (PDAC), and recent meta-analysis studies showed that metformin, reduces the risk of pancreatic cancer (PC). We tested the effects of metformin on pancreatic intrae...

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Main Authors: Mohammed, Altaf, Janakiram, Naveena B, Brewer, Misty, Ritchie, Rebekah L, Marya, Anuj, Lightfoot, Stan, Steele, Vernon E, Rao, Chinthalapally V
格式: Artigo
語言:Inglês
出版: Neoplasia Press Inc. 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890699/
https://ncbi.nlm.nih.gov/pubmed/24466367
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