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Antidiabetic Drug Metformin Prevents Progression of Pancreatic Cancer by Targeting in Part Cancer Stem Cells and mTOR Signaling

Epidemiologic studies have shown that diabetes mellitus is associated positively with increased risk of pancreatic ductal adenocarcinoma (PDAC), and recent meta-analysis studies showed that metformin, reduces the risk of pancreatic cancer (PC). We tested the effects of metformin on pancreatic intrae...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mohammed, Altaf, Janakiram, Naveena B, Brewer, Misty, Ritchie, Rebekah L, Marya, Anuj, Lightfoot, Stan, Steele, Vernon E, Rao, Chinthalapally V
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Neoplasia Press Inc. 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890699/
https://ncbi.nlm.nih.gov/pubmed/24466367
Tagiau: Ychwanegu Tag
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