Chemopreventive efficacy of raloxifene, bexarotene and their combination on the progression of chemically-induced colon adenomas to adenocarcinomas in rats

Estrogen Receptor (ER)-β signaling is associated positively in colon tumor progression, whereas down-regulation or loss of function of retinoid X receptor (RXR)-α occurs in colon tumors. The chemopreventive efficacies of the estrogen antagonist raloxifene and the selective RXR agonist bexarotene wer...

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Detalhes bibliográficos
Publicado no:Cancer Prev Res (Phila)
Main Authors: Janakiram, Naveena B., Mohammed, Altaf, Zhang, Yuting, Brewer, Misty, Bryant, Taylor, Lightfoot, Stan, Steele, Vernon E., Rao, Chinthalapally V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655595/
https://ncbi.nlm.nih.gov/pubmed/24080207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-13-0249
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