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Potentiating NK cell activity by combination of Rosuvastatin and Difluoromethylornithine for effective chemopreventive efficacy against Colon Cancer

Colorectal cancer (CRC) is the second highest cause of cancer-related deaths. A successful strategy to improve chemopreventive efficacies is by down-regulating tumor polyamines and enhancing NK cell activities. Colonic carcinogenesis was induced by azoxymethane (AOM) in male F344 rats. Eight weeks a...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Janakiram, Naveena B., Mohammed, Altaf, Bryant, Taylor, Zhang, Yuting, Brewer, Misty, Duff, Ashley, Biddick, Laura, Singh, Anil, Lightfoot, Stan, Steele, Vernon E, Rao, Chinthalapally V.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5107958/
https://ncbi.nlm.nih.gov/pubmed/27841323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37046
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