The incredible journey: From megakaryocyte development to platelet formation

Por Machlus, Kellie R., Italiano, Joseph E.
Publicado em 2013

Update on Venous Thromboembolism: Risk Factors, Mechanisms, and Treatments

Por Machlus, Kellie R., Aleman, Maria M., Wolberg, Alisa S.
Publicado em 2011

Procoagulant activity induced by vascular injury determines contribution of elevated factor VIII to thrombosis and thrombus stability in mice

Por Machlus, Kellie R., Lin, Feng-Chang, Wolberg, Alisa S.
Publicado em 2011

Procoagulant Activity in Hemostasis and Thrombosis: Virchow’s Triad Revisited

Por Wolberg, Alisa S., Aleman, Maria M., Leiderman, Karin, Machlus, Kellie R.
Publicado em 2011

Causal relationship between hyperfibrinogenemia, thrombosis, and resistance to thrombolysis in mice

Por Machlus, Kellie R., Cardenas, Jessica C., Church, Frank C., Wolberg, Alisa S.
Publicado em 2011

DETECTION OF ENDOGENOUS TISSUE FACTOR LEVELS IN PLASMA USING THE CALIBRATED AUTOMATED THROMBOGRAM ASSAY

Por Ollivier, Veronique, Wang, Jianguo, Manly, David, Machlus, Kellie R., Wolberg, Alisa S., Jandrot-Perrus, Martine, Mackman, Nigel
Publicado em 2009

Effects of tissue factor, thrombomodulin and elevated clotting factor levels on thrombin generation in the calibrated automated thrombogram

Por Machlus, Kellie R., Colby, Emily A., Wu, Jogin R., Koch, Gary G., Key, Nigel S., Wolberg, Alisa S.
Publicado em 2009

Anticoagulation inhibits tumor cell–mediated release of platelet angiogenic proteins and diminishes platelet angiogenic response

Por Battinelli, Elisabeth M., Markens, Beth A., Kulenthirarajan, Rajesh A., Machlus, Kellie R., Flaumenhaft, Robert, Italiano, Joseph E.
Publicado em 2014

Recombinant Factor VIIa Analog NN1731 (V158D/E296V/M298Q-FVIIa) Enhances Fibrin Formation, Structure and Stability in Lipidated Hemophilic Plasma

Por Gray, Laura D., Hussey, Michael A., Larson, Brittany M., Machlus, Kellie R., Campbell, Robert A., Koch, Gary, Ezban, Mirella, Hedner, Ulla, Wolberg, Alisa S.
Publicado em 2011

Elevated prothrombin promotes venous, but not arterial, thrombosis in mice

Por Aleman, Maria M., Walton, Bethany L., Byrnes, James R., Wang, Jian-Guo, Heisler, Matthew J., Machlus, Kellie R., Cooley, Brian C., Wolberg, Alisa S.
Publicado em 2013

Tamoxifen Directly Inhibits Platelet Angiogenic Potential and Platelet-Mediated Metastasis

Por Johnson, Kelly E., Forward, Jodi A., Tippy, Mason D., Ceglowski, Julia R., El-Husayni, Saleh, Kulenthirarajan, Rajesh, Machlus, Kellie R., Mayer, Erica L., Italiano, Joseph E., Battinelli, Elisabeth M.
Publicado no Arterioscler Thromb Vasc Biol (2017)

T granules in human platelets function in TLR9 organization and signaling

Por Thon, Jonathan N., Peters, Christopher G., Machlus, Kellie R., Aslam, Rukhsana, Rowley, Jesse, Macleod, Hannah, Devine, Matthew T., Fuchs, Tobias A., Weyrich, Andrew S., Semple, John W., Flaumenhaft, Robert, Italiano, Joseph E.
Publicado em 2012

Platelet bioreactor-on-a-chip

Por Thon, Jonathan N., Mazutis, Linas, Wu, Stephen, Sylman, Joanna L., Ehrlicher, Allen, Machlus, Kellie R., Feng, Qiang, Lu, Shijiang, Lanza, Robert, Neeves, Keith B., Weitz, David A., Italiano, Joseph E.
Publicado em 2014

CCL5 derived from platelets increases megakaryocyte proplatelet formation

Por Machlus, Kellie R., Johnson, Kelly E., Kulenthirarajan, Rajesh, Forward, Jodi A., Tippy, Mason D., Soussou, Thomas S., El-Husayni, Saleh H., Wu, Stephen K., Wang, Suming, Watnick, Randolph S., Italiano, Joseph E., Battinelli, Elisabeth M.
Publicado no Blood (2016)

Synthesis and dephosphorylation of MARCKS in the late stages of megakaryocyte maturation drive proplatelet formation

Por Machlus, Kellie R., Wu, Stephen K., Stumpo, Deborah J., Soussou, Thomas S., Paul, David S., Campbell, Robert A., Kalwa, Hermann, Michel, Thomas, Bergmeier, Wolfgang, Weyrich, Andrew S., Blackshear, Perry J., Hartwig, John H., Italiano, Joseph E.
Publicado no Blood (2016)

Scalable Generation of Universal Platelets from Human Induced Pluripotent Stem Cells

Por Feng, Qiang, Shabrani, Namrata, Thon, Jonathan N., Huo, Hongguang, Thiel, Austin, Machlus, Kellie R., Kim, Kyungho, Brooks, Julie, Li, Feng, Luo, Chenmei, Kimbrel, Erin A., Wang, Jiwu, Kim, Kwang-Soo, Italiano, Joseph, Cho, Jaehyung, Lu, Shi-Jiang, Lanza, Robert
Publicado no Stem Cell Reports (2014)

Inducible Gata1 suppression expands megakaryocyte-erythroid progenitors from embryonic stem cells

Por Noh, Ji-Yoon, Gandre-Babbe, Shilpa, Wang, Yuhuan, Hayes, Vincent, Yao, Yu, Gadue, Paul, Sullivan, Spencer K., Chou, Stella T., Machlus, Kellie R., Italiano, Joseph E., Kyba, Michael, Finkelstein, David, Ulirsch, Jacob C., Sankaran, Vijay G., French, Deborah L., Poncz, Mortimer, Weiss, Mitchell J.
Publicado no J Clin Invest (2015)

Proteasome function is required for platelet production

Por Shi, Dallas S., Smith, Matthew C.P., Campbell, Robert A., Zimmerman, Patrick W., Franks, Zechariah B., Kraemer, Bjorn F., Machlus, Kellie R., Ling, Jing, Kamba, Patrick, Schwertz, Hansjörg, Rowley, Jesse W., Miles, Rodney R., Liu, Zhi-Jian, Sola-Visner, Martha, Italiano, Joseph E., Christensen, Hilary, Kahr, Walter H.A., Li, Dean Y., Weyrich, Andrew S.
Publicado em 2014