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Causal relationship between hyperfibrinogenemia, thrombosis, and resistance to thrombolysis in mice

Epidemiologic studies have correlated elevated plasma fibrinogen (hyperfibrinogenemia) with risk of cardiovascular disease and arterial and venous thrombosis. However, it is unknown whether hyperfibrinogenemia is merely a biomarker of the proinflammatory disease state or is a causative mechanism in...

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Hlavní autoři: Machlus, Kellie R., Cardenas, Jessica C., Church, Frank C., Wolberg, Alisa S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100702/
https://ncbi.nlm.nih.gov/pubmed/21355090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-11-316885
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