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Causal relationship between hyperfibrinogenemia, thrombosis, and resistance to thrombolysis in mice

Epidemiologic studies have correlated elevated plasma fibrinogen (hyperfibrinogenemia) with risk of cardiovascular disease and arterial and venous thrombosis. However, it is unknown whether hyperfibrinogenemia is merely a biomarker of the proinflammatory disease state or is a causative mechanism in...

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Библиографические подробности
Главные авторы: Machlus, Kellie R., Cardenas, Jessica C., Church, Frank C., Wolberg, Alisa S.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Hematology 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100702/
https://ncbi.nlm.nih.gov/pubmed/21355090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-11-316885
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