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Causal relationship between hyperfibrinogenemia, thrombosis, and resistance to thrombolysis in mice

Epidemiologic studies have correlated elevated plasma fibrinogen (hyperfibrinogenemia) with risk of cardiovascular disease and arterial and venous thrombosis. However, it is unknown whether hyperfibrinogenemia is merely a biomarker of the proinflammatory disease state or is a causative mechanism in...

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Detalhes bibliográficos
Main Authors: Machlus, Kellie R., Cardenas, Jessica C., Church, Frank C., Wolberg, Alisa S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100702/
https://ncbi.nlm.nih.gov/pubmed/21355090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-11-316885
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