Tumor-derived tissue factor activates coagulation and enhances thrombosis in a mouse xenograft model of human pancreatic cancer

Cancer patients often have an activated clotting system and are at increased risk for venous thrombosis. In the present study, we analyzed tissue factor (TF) expression in 4 different human pancreatic tumor cell lines for the purpose of producing derivative tumors in vivo. We found that 2 of the lin...

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Bibliografiset tiedot
Päätekijät: Wang, Jian-Guo, Geddings, Julia E., Aleman, Maria M., Cardenas, Jessica C., Chantrathammachart, Pichika, Williams, Julie C., Kirchhofer, Daniel, Bogdanov, Vladimir Y., Bach, Ronald R., Rak, Janusz, Church, Frank C., Wolberg, Alisa S., Pawlinski, Rafal, Key, Nigel S., Yeh, Jen Jen, Mackman, Nigel
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Hematology 2012
Aiheet:
Thrombosis and Hemostasis
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369688/
https://ncbi.nlm.nih.gov/pubmed/22547577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-01-402156
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