Tumor-derived tissue factor activates coagulation and enhances thrombosis in a mouse xenograft model of human pancreatic cancer

Cancer patients often have an activated clotting system and are at increased risk for venous thrombosis. In the present study, we analyzed tissue factor (TF) expression in 4 different human pancreatic tumor cell lines for the purpose of producing derivative tumors in vivo. We found that 2 of the lin...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wang, Jian-Guo, Geddings, Julia E., Aleman, Maria M., Cardenas, Jessica C., Chantrathammachart, Pichika, Williams, Julie C., Kirchhofer, Daniel, Bogdanov, Vladimir Y., Bach, Ronald R., Rak, Janusz, Church, Frank C., Wolberg, Alisa S., Pawlinski, Rafal, Key, Nigel S., Yeh, Jen Jen, Mackman, Nigel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2012
Gaiak:
Thrombosis and Hemostasis
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369688/
https://ncbi.nlm.nih.gov/pubmed/22547577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-01-402156
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