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Differential contribution of FXa and thrombin to vascular inflammation in a mouse model of sickle cell disease
Activation of coagulation and vascular inflammation are prominent features of sickle cell disease (SCD). Previously, we have shown that inhibition of tissue factor (TF) attenuates activation of coagulation and vascular inflammation in mouse models of SCD. In this study, we examined the mechanism by...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Hematology
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3954055/ https://ncbi.nlm.nih.gov/pubmed/24449213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-08-523936 |
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