Tissue factor promotes activation of coagulation and inflammation in a mouse model of sickle cell disease

Sickle cell disease (SCD) is associated with a complex vascular pathophysiology that includes activation of coagulation and inflammation. However, the crosstalk between these 2 systems in SCD has not been investigated. Here, we examined the role of tissue factor (TF) in the activation of coagulation...

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Hlavní autoři: Chantrathammachart, Pichika, Mackman, Nigel, Sparkenbaugh, Erica, Wang, Jian-Guo, Parise, Leslie V., Kirchhofer, Daniel, Key, Nigel S., Pawlinski, Rafal
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2012
Témata:
Red Cells, Iron, and Erythropoiesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401215/
https://ncbi.nlm.nih.gov/pubmed/22661702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-04-424143
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