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Causal relationship between hyperfibrinogenemia, thrombosis, and resistance to thrombolysis in mice

Epidemiologic studies have correlated elevated plasma fibrinogen (hyperfibrinogenemia) with risk of cardiovascular disease and arterial and venous thrombosis. However, it is unknown whether hyperfibrinogenemia is merely a biomarker of the proinflammatory disease state or is a causative mechanism in...

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Détails bibliographiques
Auteurs principaux: Machlus, Kellie R., Cardenas, Jessica C., Church, Frank C., Wolberg, Alisa S.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100702/
https://ncbi.nlm.nih.gov/pubmed/21355090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-11-316885
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