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Procoagulant activity induced by vascular injury determines contribution of elevated factor VIII to thrombosis and thrombus stability in mice

Studies have correlated elevated plasma factor VIII (FVIII) with thrombosis; however, it is unclear whether elevated FVIII is a proinflammatory biomarker, causative agent, or both. We raised FVIII levels in mice and measured the time to vessel occlusion (TTO) after ferric chloride–induced injury. Co...

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書誌詳細
主要な著者: Machlus, Kellie R., Lin, Feng-Chang, Wolberg, Alisa S.
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193271/
https://ncbi.nlm.nih.gov/pubmed/21828144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-06-362814
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