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Proteasome function is required for platelet production
The proteasome inhibiter bortezomib has been successfully used to treat patients with relapsed multiple myeloma; however, many of these patients become thrombocytopenic, and it is not clear how the proteasome influences platelet production. Here we determined that pharmacologic inhibition of proteas...
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| Autores principales: | , , , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4151230/ https://ncbi.nlm.nih.gov/pubmed/25061876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI75247 |
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