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Granzyme A in Human Platelets Regulates the Synthesis of Pro-Inflammatory Cytokines by Monocytes in Aging
Dysregulated inflammation is implicated in the pathobiology of aging, yet platelet-leukocyte interactions and downstream cytokine synthesis in aging remains poorly understood. Platelets and monocytes were isolated from healthy younger (age<45, n=37) and older (age≥65, n=30) adults and incubated t...
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| Publicado en: | J Immunol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5736423/ https://ncbi.nlm.nih.gov/pubmed/29167233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700885 |
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