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Granzyme A in Human Platelets Regulates the Synthesis of Pro-Inflammatory Cytokines by Monocytes in Aging

Dysregulated inflammation is implicated in the pathobiology of aging, yet platelet-leukocyte interactions and downstream cytokine synthesis in aging remains poorly understood. Platelets and monocytes were isolated from healthy younger (age<45, n=37) and older (age≥65, n=30) adults and incubated t...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Immunol
Päätekijät: Campbell, Robert A., Franks, Zechariah, Bhatnagar, Anish, Rowley, Jesse W., Manne, Bhanu K., Supiano, Mark A., Schwertz, Hansjorg, Weyrich, Andrew S., Rondina, Matthew T.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5736423/
https://ncbi.nlm.nih.gov/pubmed/29167233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700885
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