CCL5 derived from platelets increases megakaryocyte proplatelet formation

In times of physiological stress, platelet count can transiently rise. What initiates this reactive thrombocytosis is poorly understood. Intriguingly, we found that treating megakaryocytes (MKs) with the releasate from activated platelets increased proplatelet production by 47%. Platelets store infl...

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Bibliografski detalji
Izdano u:Blood
Glavni autori: Machlus, Kellie R., Johnson, Kelly E., Kulenthirarajan, Rajesh, Forward, Jodi A., Tippy, Mason D., Soussou, Thomas S., El-Husayni, Saleh H., Wu, Stephen K., Wang, Suming, Watnick, Randolph S., Italiano, Joseph E., Battinelli, Elisabeth M.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2016
Teme:
Platelets and Thrombopoiesis
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760093/
https://ncbi.nlm.nih.gov/pubmed/26647394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-05-644583
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