CCL5 derived from platelets increases megakaryocyte proplatelet formation

In times of physiological stress, platelet count can transiently rise. What initiates this reactive thrombocytosis is poorly understood. Intriguingly, we found that treating megakaryocytes (MKs) with the releasate from activated platelets increased proplatelet production by 47%. Platelets store infl...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Machlus, Kellie R., Johnson, Kelly E., Kulenthirarajan, Rajesh, Forward, Jodi A., Tippy, Mason D., Soussou, Thomas S., El-Husayni, Saleh H., Wu, Stephen K., Wang, Suming, Watnick, Randolph S., Italiano, Joseph E., Battinelli, Elisabeth M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2016
Assuntos:
Platelets and Thrombopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760093/
https://ncbi.nlm.nih.gov/pubmed/26647394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-05-644583
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