The spectrin-based membrane skeleton stabilizes mouse megakaryocyte membrane systems and is essential for proplatelet and platelet formation

Megakaryocytes generate platelets by remodeling their cytoplasm first into proplatelets and then into preplatelets, which undergo fission to generate platelets. Although the functions of microtubules and actin during platelet biogenesis have been defined, the role of the spectrin cytoskeleton is unk...

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Bibliographische Detailangaben
Hauptverfasser: Patel-Hett, Sunita, Wang, Hongbei, Begonja, Antonija J., Thon, Jonathan N., Alden, Eva C., Wandersee, Nancy J., An, Xiuli, Mohandas, Narla, Hartwig, John H., Italiano, Joseph E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2011
Schlagworte:
Platelets and Thrombopoiesis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156050/
https://ncbi.nlm.nih.gov/pubmed/21566095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-01-330688
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