Canonical Wnt signaling in megakaryocytes regulates proplatelet formation

Wnt signaling is involved in numerous aspects of vertebrate development and homeostasis, including the formation and function of blood cells. Here, we show that canonical and noncanonical Wnt signaling pathways are present and functional in megakaryocytes (MKs), with several Wnt effectors displaying...

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Detalhes bibliográficos
Main Authors: Macaulay, Iain C., Thon, Jonathan N., Tijssen, Marloes R., Steele, Brian M., MacDonald, Bryan T., Meade, Gerardene, Burns, Philippa, Rendon, Augusto, Salunkhe, Vishal, Murphy, Ronan P., Bennett, Cavan, Watkins, Nicholas A., He, Xi, Fitzgerald, Desmond J., Italiano, Joseph E., Maguire, Patricia B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
Assuntos:
Platelets and Thrombopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538329/
https://ncbi.nlm.nih.gov/pubmed/23160460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-03-416875
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