Canonical Wnt signaling in megakaryocytes regulates proplatelet formation

Wnt signaling is involved in numerous aspects of vertebrate development and homeostasis, including the formation and function of blood cells. Here, we show that canonical and noncanonical Wnt signaling pathways are present and functional in megakaryocytes (MKs), with several Wnt effectors displaying...

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Detalles Bibliográficos
Main Authors: Macaulay, Iain C., Thon, Jonathan N., Tijssen, Marloes R., Steele, Brian M., MacDonald, Bryan T., Meade, Gerardene, Burns, Philippa, Rendon, Augusto, Salunkhe, Vishal, Murphy, Ronan P., Bennett, Cavan, Watkins, Nicholas A., He, Xi, Fitzgerald, Desmond J., Italiano, Joseph E., Maguire, Patricia B.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2013
Assuntos:
Platelets and Thrombopoiesis
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538329/
https://ncbi.nlm.nih.gov/pubmed/23160460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-03-416875
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