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Microtubule sliding drives proplatelet elongation and is dependent on cytoplasmic dynein

Bone marrow megakaryocytes produce platelets by extending long cytoplasmic protrusions, designated proplatelets, into sinusoidal blood vessels. Although microtubules are known to regulate platelet production, the underlying mechanism of proplatelet elongation has yet to be resolved. Here we report t...

詳細記述

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書誌詳細
出版年:Blood
主要な著者: Bender, Markus, Thon, Jonathan N., Ehrlicher, Allen J., Wu, Stephen, Mazutis, Linas, Deschmann, Emoke, Sola-Visner, Martha, Italiano, Joseph E., Hartwig, John H.
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4311231/
https://ncbi.nlm.nih.gov/pubmed/25411426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-09-600858
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