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Microtubule sliding drives proplatelet elongation and is dependent on cytoplasmic dynein
Bone marrow megakaryocytes produce platelets by extending long cytoplasmic protrusions, designated proplatelets, into sinusoidal blood vessels. Although microtubules are known to regulate platelet production, the underlying mechanism of proplatelet elongation has yet to be resolved. Here we report t...
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| 出版年: | Blood |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Hematology
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4311231/ https://ncbi.nlm.nih.gov/pubmed/25411426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-09-600858 |
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