Canonical Wnt signaling in megakaryocytes regulates proplatelet formation

Wnt signaling is involved in numerous aspects of vertebrate development and homeostasis, including the formation and function of blood cells. Here, we show that canonical and noncanonical Wnt signaling pathways are present and functional in megakaryocytes (MKs), with several Wnt effectors displaying...

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Detaylı Bibliyografya
Asıl Yazarlar: Macaulay, Iain C., Thon, Jonathan N., Tijssen, Marloes R., Steele, Brian M., MacDonald, Bryan T., Meade, Gerardene, Burns, Philippa, Rendon, Augusto, Salunkhe, Vishal, Murphy, Ronan P., Bennett, Cavan, Watkins, Nicholas A., He, Xi, Fitzgerald, Desmond J., Italiano, Joseph E., Maguire, Patricia B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2013
Konular:
Platelets and Thrombopoiesis
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538329/
https://ncbi.nlm.nih.gov/pubmed/23160460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-03-416875
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