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Anticoagulation inhibits tumor cell–mediated release of platelet angiogenic proteins and diminishes platelet angiogenic response

Platelets are a reservoir for angiogenic proteins that are secreted in a differentially regulated process. Because of the propensity for clotting, patients with malignancy are often anticoagulated with heparin products, which paradoxically offer a survival benefit by an unknown mechanism. We hypothe...

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Detalhes bibliográficos
Main Authors: Battinelli, Elisabeth M., Markens, Beth A., Kulenthirarajan, Rajesh A., Machlus, Kellie R., Flaumenhaft, Robert, Italiano, Joseph E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879901/
https://ncbi.nlm.nih.gov/pubmed/24065244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-02-485011
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