CCL5 derived from platelets increases megakaryocyte proplatelet formation

In times of physiological stress, platelet count can transiently rise. What initiates this reactive thrombocytosis is poorly understood. Intriguingly, we found that treating megakaryocytes (MKs) with the releasate from activated platelets increased proplatelet production by 47%. Platelets store infl...

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Dades bibliogràfiques
Publicat a:Blood
Autors principals: Machlus, Kellie R., Johnson, Kelly E., Kulenthirarajan, Rajesh, Forward, Jodi A., Tippy, Mason D., Soussou, Thomas S., El-Husayni, Saleh H., Wu, Stephen K., Wang, Suming, Watnick, Randolph S., Italiano, Joseph E., Battinelli, Elisabeth M.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2016
Matèries:
Platelets and Thrombopoiesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760093/
https://ncbi.nlm.nih.gov/pubmed/26647394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-05-644583
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