T granules in human platelets function in TLR9 organization and signaling

Human and murine platelets (PLTs) variably express toll-like receptors (TLRs), which link the innate and adaptive immune responses during infectious inflammation and atherosclerotic vascular disease. In this paper, we show that the TLR9 transcript is specifically up-regulated during pro-PLT producti...

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Detalhes bibliográficos
Main Authors: Thon, Jonathan N., Peters, Christopher G., Machlus, Kellie R., Aslam, Rukhsana, Rowley, Jesse, Macleod, Hannah, Devine, Matthew T., Fuchs, Tobias A., Weyrich, Andrew S., Semple, John W., Flaumenhaft, Robert, Italiano, Joseph E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3514030/
https://ncbi.nlm.nih.gov/pubmed/22908309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201111136
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