A genetic screen for neurite outgrowth mutants in Caenorhabditis elegans reveals a new function for the F-box ubiquitin ligase component LIN-23.

di Mehta, Nehal, Loria, Paula M, Hobert, Oliver
Pubblicazione 2004

A Conserved Postsynaptic Transmembrane Protein Affecting Neuromuscular Signaling in Caenorhabditis elegans

di Loria, Paula M., Hodgkin, Jonathan, Hobert, Oliver
Pubblicato in J Neurosci (2004)

Modulation of αCaMKII signaling by rapid ERα action

di O’Neill, Erin E., Blewett, Alexis R., Loria, Paula M., Greene, Geoffrey L.
Pubblicazione 2008

Discovery of Diphenylacetamides as CXCR7 Inhibitors with Novel β-Arrestin Antagonist Activity

di Menhaji-Klotz, Elnaz, Ward, Jessica, Brown, Janice A., Loria, Paula M., Tan, Carina, Hesp, Kevin D., Riccardi, Keith A., Litchfield, John, Boehm, Markus
Pubblicato in ACS Med Chem Lett (2020)

Antibody-Directed Myostatin Inhibition Improves Diaphragm Pathology in Young but not Adult Dystrophic mdx Mice

di Murphy, Kate T., Ryall, James G., Snell, Sarah M., Nair, Lawrence, Koopman, René, Krasney, Philip A., Ibebunjo, Chikwendu, Holden, Kathryn S., Loria, Paula M., Salatto, Christopher T., Lynch, Gordon S.
Pubblicazione 2010

The use of plasma aldosterone and urinary sodium to potassium ratio as translatable quantitative biomarkers of mineralocorticoid receptor antagonism

di Eudy, Rena J, Sahasrabudhe, Vaishali, Sweeney, Kevin, Tugnait, Meera, King-Ahmad, Amanda, Near, Kristen, Loria, Paula, Banker, Mary Ellen, Piotrowski, David W, Boustany-Kari, Carine M
Pubblicazione 2011

PF-03882845, a non-steroidal mineralocorticoid receptor antagonist, prevents renal injury with reduced risk of hyperkalemia in an animal model of nephropathy

di Orena, Stephen, Maurer, Tristan S., She, Li, Eudy, Rena, Bernardo, Vincent, Dash, Darla, Loria, Paula, Banker, Mary E., Tugnait, Meera, Okerberg, Carlin V., Qian, Jessie, Boustany-Kari, Carine M.
Pubblicazione 2013

Truncated Glucagon-like Peptide-1 and Exendin-4 α-Conotoxin pl14a Peptide Chimeras Maintain Potency and α-Helicity and Reveal Interactions Vital for cAMP Signaling in Vitro

di Swedberg, Joakim E., Schroeder, Christina I., Mitchell, Justin M., Fairlie, David P., Edmonds, David J., Griffith, David A., Ruggeri, Roger B., Derksen, David R., Loria, Paula M., Price, David A., Liras, Spiros, Craik, David J.
Pubblicato in J Biol Chem (2016)

Discovery of Orally Bioavailable Selective Inhibitors of the Sodium-Phosphate Cotransporter NaPi2a (SLC34A1)

di Filipski, Kevin J., Sammons, Matthew F., Bhattacharya, Samit K., Panteleev, Jane, Brown, Janice A., Loria, Paula M., Boehm, Markus, Smith, Aaron C., Shavnya, Andre, Conn, Edward L., Song, Kun, Weng, Yan, Facemire, Carie, Jüppner, Harald, Clerin, Valerie
Pubblicato in ACS Med Chem Lett (2018)

Selective stalling of human translation through small-molecule engagement of the ribosome nascent chain

di Lintner, Nathanael G., McClure, Kim F., Petersen, Donna, Londregan, Allyn T., Piotrowski, David W., Wei, Liuqing, Xiao, Jun, Bolt, Michael, Loria, Paula M., Maguire, Bruce, Geoghegan, Kieran F., Huang, Austin, Rolph, Tim, Liras, Spiros, Doudna, Jennifer A., Dullea, Robert G., Cate, Jamie H. D.
Pubblicato in PLoS Biol (2017)

Correction: Selective stalling of human translation through small-molecule engagement of the ribosome nascent chain

di Lintner, Nathanael G., McClure, Kim F., Petersen, Donna, Londregan, Allyn T., Piotrowski, David W., Wei, Liuqing, Xiao, Jun, Bolt, Michael, Loria, Paula M., Maguire, Bruce, Geoghegan, Kieran F., Huang, Austin, Rolph, Tim, Liras, Spiros, Doudna, Jennifer A., Dullea, Robert G., Cate, Jamie H. D.
Pubblicato in PLoS Biol (2018)

Chemical Probe Identification Platform for Orphan GPCRs Using Focused Compound Screening: GPR39 as a Case Example

di Boehm, Markus, Hepworth, David, Loria, Paula M., Norquay, Lisa D., Filipski, Kevin J., Chin, Janice E., Cameron, Kimberly O., Brenner, Martin, Bonnette, Peter, Cabral, Shawn, Conn, Edward, Ebner, David C., Gautreau, Denise, Hadcock, John, Lee, Esther C. Y., Mathiowetz, Alan M., Morin, Michelle, Rogers, Lucy, Smith, Aaron, VanVolkenburg, Maria, Carpino, Philip A.
Pubblicazione 2013

Evaluation and Synthesis of Polar Aryl- and Heteroaryl Spiroazetidine-Piperidine Acetamides as Ghrelin Inverse Agonists

di Orr, Suvi T. M., Beveridge, Ramsay, Bhattacharya, Samit K., Cameron, Kimberly O., Coffey, Steven, Fernando, Dilinie, Hepworth, David, Jackson, Margaret V., Khot, Vishal, Kosa, Rachel, Lapham, Kimberly, Loria, Paula M., McClure, Kim F., Patel, Jigna, Rose, Colin, Saenz, James, Stock, Ingrid A., Storer, Gregory, von Volkenburg, Maria, Vrieze, Derek, Wang, Guoqiang, Xiao, Jun, Zhang, Yingxin
Pubblicato in ACS Med Chem Lett (2014)

Discovery of PF-5190457, a Potent, Selective, and Orally Bioavailable Ghrelin Receptor Inverse Agonist Clinical Candidate

di Bhattacharya, Samit K., Andrews, Kim, Beveridge, Ramsay, Cameron, Kimberly O., Chen, Chiliu, Dunn, Matthew, Fernando, Dilinie, Gao, Hua, Hepworth, David, Jackson, V. Margaret, Khot, Vishal, Kong, Jimmy, Kosa, Rachel E., Lapham, Kimberly, Loria, Paula M., Londregan, Allyn T., McClure, Kim F., Orr, Suvi T. M., Patel, Jigna, Rose, Colin, Saenz, James, Stock, Ingrid A., Storer, Gregory, VanVolkenburg, Maria, Vrieze, Derek, Wang, Guoqiang, Xiao, Jun, Zhang, Yingxin
Pubblicazione 2014

Discovery of an in Vivo Tool to Establish Proof-of-Concept for MAP4K4-Based Antidiabetic Treatment

di Ammirati, Mark, Bagley, Scott W., Bhattacharya, Samit K., Buckbinder, Leonard, Carlo, Anthony A., Conrad, Rebecca, Cortes, Christian, Dow, Robert L., Dowling, Matthew S., El-Kattan, Ayman, Ford, Kristen, Guimarães, Cristiano R. W., Hepworth, David, Jiao, Wenhua, LaPerle, Jennifer, Liu, Shenping, Londregan, Allyn, Loria, Paula M., Mathiowetz, Alan M., Munchhof, Michael, Orr, Suvi T. M., Petersen, Donna N., Price, David A., Skoura, Athanasia, Smith, Aaron C., Wang, Jian
Pubblicato in ACS Med Chem Lett (2015)

Discovery and characterization of novel inhibitors of the sodium-coupled citrate transporter (NaCT or SLC13A5)

di Huard, Kim, Brown, Janice, Jones, Jessica C., Cabral, Shawn, Futatsugi, Kentaro, Gorgoglione, Matthew, Lanba, Adhiraj, Vera, Nicholas B., Zhu, Yimin, Yan, Qingyun, Zhou, Yingjiang, Vernochet, Cecile, Riccardi, Keith, Wolford, Angela, Pirman, David, Niosi, Mark, Aspnes, Gary, Herr, Michael, Genung, Nathan E., Magee, Thomas V., Uccello, Daniel P., Loria, Paula, Di, Li, Gosset, James R., Hepworth, David, Rolph, Timothy, Pfefferkorn, Jeffrey A., Erion, Derek M.
Pubblicato in Sci Rep (2015)