A genetic screen for neurite outgrowth mutants in Caenorhabditis elegans reveals a new function for the F-box ubiquitin ligase component LIN-23.

Por Mehta, Nehal, Loria, Paula M, Hobert, Oliver
Publicado em 2004

Modulation of αCaMKII signaling by rapid ERα action

Por O’Neill, Erin E., Blewett, Alexis R., Loria, Paula M., Greene, Geoffrey L.
Publicado em 2008

Antibody-Directed Myostatin Inhibition Improves Diaphragm Pathology in Young but not Adult Dystrophic mdx Mice

Por Murphy, Kate T., Ryall, James G., Snell, Sarah M., Nair, Lawrence, Koopman, René, Krasney, Philip A., Ibebunjo, Chikwendu, Holden, Kathryn S., Loria, Paula M., Salatto, Christopher T., Lynch, Gordon S.
Publicado em 2010

Truncated Glucagon-like Peptide-1 and Exendin-4 α-Conotoxin pl14a Peptide Chimeras Maintain Potency and α-Helicity and Reveal Interactions Vital for cAMP Signaling in Vitro

Por Swedberg, Joakim E., Schroeder, Christina I., Mitchell, Justin M., Fairlie, David P., Edmonds, David J., Griffith, David A., Ruggeri, Roger B., Derksen, David R., Loria, Paula M., Price, David A., Liras, Spiros, Craik, David J.
Publicado no J Biol Chem (2016)

Selective stalling of human translation through small-molecule engagement of the ribosome nascent chain

Por Lintner, Nathanael G., McClure, Kim F., Petersen, Donna, Londregan, Allyn T., Piotrowski, David W., Wei, Liuqing, Xiao, Jun, Bolt, Michael, Loria, Paula M., Maguire, Bruce, Geoghegan, Kieran F., Huang, Austin, Rolph, Tim, Liras, Spiros, Doudna, Jennifer A., Dullea, Robert G., Cate, Jamie H. D.
Publicado no PLoS Biol (2017)

Chemical Probe Identification Platform for Orphan GPCRs Using Focused Compound Screening: GPR39 as a Case Example

Por Boehm, Markus, Hepworth, David, Loria, Paula M., Norquay, Lisa D., Filipski, Kevin J., Chin, Janice E., Cameron, Kimberly O., Brenner, Martin, Bonnette, Peter, Cabral, Shawn, Conn, Edward, Ebner, David C., Gautreau, Denise, Hadcock, John, Lee, Esther C. Y., Mathiowetz, Alan M., Morin, Michelle, Rogers, Lucy, Smith, Aaron, VanVolkenburg, Maria, Carpino, Philip A.
Publicado em 2013

Evaluation and Synthesis of Polar Aryl- and Heteroaryl Spiroazetidine-Piperidine Acetamides as Ghrelin Inverse Agonists

Por Orr, Suvi T. M., Beveridge, Ramsay, Bhattacharya, Samit K., Cameron, Kimberly O., Coffey, Steven, Fernando, Dilinie, Hepworth, David, Jackson, Margaret V., Khot, Vishal, Kosa, Rachel, Lapham, Kimberly, Loria, Paula M., McClure, Kim F., Patel, Jigna, Rose, Colin, Saenz, James, Stock, Ingrid A., Storer, Gregory, von Volkenburg, Maria, Vrieze, Derek, Wang, Guoqiang, Xiao, Jun, Zhang, Yingxin
Publicado no ACS Med Chem Lett (2014)

Discovery of PF-5190457, a Potent, Selective, and Orally Bioavailable Ghrelin Receptor Inverse Agonist Clinical Candidate

Por Bhattacharya, Samit K., Andrews, Kim, Beveridge, Ramsay, Cameron, Kimberly O., Chen, Chiliu, Dunn, Matthew, Fernando, Dilinie, Gao, Hua, Hepworth, David, Jackson, V. Margaret, Khot, Vishal, Kong, Jimmy, Kosa, Rachel E., Lapham, Kimberly, Loria, Paula M., Londregan, Allyn T., McClure, Kim F., Orr, Suvi T. M., Patel, Jigna, Rose, Colin, Saenz, James, Stock, Ingrid A., Storer, Gregory, VanVolkenburg, Maria, Vrieze, Derek, Wang, Guoqiang, Xiao, Jun, Zhang, Yingxin
Publicado em 2014

Discovery of an in Vivo Tool to Establish Proof-of-Concept for MAP4K4-Based Antidiabetic Treatment

Por Ammirati, Mark, Bagley, Scott W., Bhattacharya, Samit K., Buckbinder, Leonard, Carlo, Anthony A., Conrad, Rebecca, Cortes, Christian, Dow, Robert L., Dowling, Matthew S., El-Kattan, Ayman, Ford, Kristen, Guimarães, Cristiano R. W., Hepworth, David, Jiao, Wenhua, LaPerle, Jennifer, Liu, Shenping, Londregan, Allyn, Loria, Paula M., Mathiowetz, Alan M., Munchhof, Michael, Orr, Suvi T. M., Petersen, Donna N., Price, David A., Skoura, Athanasia, Smith, Aaron C., Wang, Jian
Publicado no ACS Med Chem Lett (2015)