Evaluation of Cu-64 and Ga-68 Radiolabeled Glucagon-Like Peptide-1 Receptor Agonists as PET Tracers for Pancreatic β cell Imaging

Por Bandara, Nilantha, Zheleznyak, Alex, Cherukuri, Kaavya, Griffith, David A., Limberakis, Chris, Tess, David A., Jianqing, Chen, Waterhouse, Rikki, Lapi, Suzanne E.
Publicado no Mol Imaging Biol (2016)

Pharmacodynamic Model of Parathyroid Hormone Modulation by a Negative Allosteric Modulator of the Calcium-Sensing Receptor

Por Abraham, Anson K., Maurer, Tristan S., Kalgutkar, Amit S., Gao, Xiang, Li, Mei, Healy, David R., Petersen, Donna N., Griffith, David A., Mager, Donald E.
Publicado em 2011

Truncated Glucagon-like Peptide-1 and Exendin-4 α-Conotoxin pl14a Peptide Chimeras Maintain Potency and α-Helicity and Reveal Interactions Vital for cAMP Signaling in Vitro

Por Swedberg, Joakim E., Schroeder, Christina I., Mitchell, Justin M., Fairlie, David P., Edmonds, David J., Griffith, David A., Ruggeri, Roger B., Derksen, David R., Loria, Paula M., Price, David A., Liras, Spiros, Craik, David J.
Publicado no J Biol Chem (2016)

Quantitative in vitro and in vivo pharmacological profile of CE-178253, a potent and selective cannabinoid type 1 (CB(1)) Receptor Antagonist

Por Hadcock, John R, Carpino, Philip A, Iredale, Philip A, Dow, Robert L, Gautreau, Denise, Thiede, Lucinda, Kelly-Sullivan, Dawn, Lizano, Jeffrey S, Liu, Xingrong, Van Deusen, Jeffrey, Ward, Karen M, O'Connor, Rebecca E, Black, Shawn C, Griffith, David A, Scott, Dennis O
Publicado em 2010

Decreasing the Rate of Metabolic Ketone Reduction in the Discovery of a Clinical Acetyl-CoA Carboxylase Inhibitor for the Treatment of Diabetes

Por Griffith, David A., Kung, Daniel W., Esler, William P., Amor, Paul A., Bagley, Scott W., Beysen, Carine, Carvajal-Gonzalez, Santos, Doran, Shawn D., Limberakis, Chris, Mathiowetz, Alan M., McPherson, Kirk, Price, David A., Ravussin, Eric, Sonnenberg, Gabriele E., Southers, James A., Sweet, Laurel J., Turner, Scott M., Vajdos, Felix F.
Publicado no J Med Chem (2014)

Cyclic Penta- and Hexaleucine Peptides without N-Methylation Are Orally Absorbed

Por Hill, Timothy A., Lohman, Rink-Jan, Hoang, Huy N., Nielsen, Daniel S., Scully, Conor C. G., Kok, W. Mei, Liu, Ligong, Lucke, Andrew J., Stoermer, Martin J., Schroeder, Christina I., Chaousis, Stephanie, Colless, Barbara, Bernhardt, Paul V., Edmonds, David J., Griffith, David A., Rotter, Charles J., Ruggeri, Roger B., Price, David A., Liras, Spiros, Craik, David J., Fairlie, David P.
Publicado em 2014