Mechanism-Based Pharmacokinetic Modeling to Evaluate Transporter-Enzyme Interplay in Drug Interactions and Pharmacogenetics of Glyburide

Por Varma, Manthena V. S., Scialis, Renato J., Lin, Jian, Bi, Yi-An, Rotter, Charles J., Goosen, Theunis C., Yang, Xin
Publicado em 2014

Optimizing PK properties of cyclic peptides: the effect of side chain substitutions on permeability and clearance()

Por Rand, Arthur C., Leung, Siegfried S. F., Eng, Heather, Rotter, Charles J., Sharma, Raman, Kalgutkar, Amit S., Zhang, Yizhong, Varma, Manthena V., Farley, Kathleen A., Khunte, Bhagyashree, Limberakis, Chris, Price, David A., Liras, Spiros, Mathiowetz, Alan M., Jacobson, Matthew P., Lokey, R. Scott
Publicado em 2012

Cyclic Penta- and Hexaleucine Peptides without N-Methylation Are Orally Absorbed

Por Hill, Timothy A., Lohman, Rink-Jan, Hoang, Huy N., Nielsen, Daniel S., Scully, Conor C. G., Kok, W. Mei, Liu, Ligong, Lucke, Andrew J., Stoermer, Martin J., Schroeder, Christina I., Chaousis, Stephanie, Colless, Barbara, Bernhardt, Paul V., Edmonds, David J., Griffith, David A., Rotter, Charles J., Ruggeri, Roger B., Price, David A., Liras, Spiros, Craik, David J., Fairlie, David P.
Publicado em 2014