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Evaluation of Cu-64 and Ga-68 Radiolabeled Glucagon-Like Peptide-1 Receptor Agonists as PET Tracers for Pancreatic β cell Imaging

PURPOSE: Copper-64 (Cu-64) and Galium-68 (Ga-68) radiolabeled DO3A and NODA conjugates of exendin-4 were used for preclinical imaging of pancreatic β cells via targeting of glucagon-like peptide-1 receptor (GLP-1R). PROCEDURES: DO3A-VS- and NODA-VS-tagged Cys(40)exendin-4 (DO3A-VS-Cys(40)-exendin-4...

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Bibliografiska uppgifter
I publikationen:Mol Imaging Biol
Huvudupphovsmän: Bandara, Nilantha, Zheleznyak, Alex, Cherukuri, Kaavya, Griffith, David A., Limberakis, Chris, Tess, David A., Jianqing, Chen, Waterhouse, Rikki, Lapi, Suzanne E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4877185/
https://ncbi.nlm.nih.gov/pubmed/25987465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-015-0861-5
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