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Discovery of Diphenylacetamides as CXCR7 Inhibitors with Novel β-Arrestin Antagonist Activity

[Image: see text] The atypical chemokine receptor CXCR7 has been studied in various disease settings including immunological diseases and heart disease. Efforts to elucidate the role of CXCR7 have been limited by the lack of suitable chemical tools with a range of pharmacological profiles. A high-th...

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Detalhes bibliográficos
Publicado no:ACS Med Chem Lett
Main Authors: Menhaji-Klotz, Elnaz, Ward, Jessica, Brown, Janice A., Loria, Paula M., Tan, Carina, Hesp, Kevin D., Riccardi, Keith A., Litchfield, John, Boehm, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7294705/
https://ncbi.nlm.nih.gov/pubmed/32551020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.0c00163
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