Discovery of Diphenylacetamides as CXCR7 Inhibitors with Novel β-Arrestin Antagonist Activity

[Image: see text] The atypical chemokine receptor CXCR7 has been studied in various disease settings including immunological diseases and heart disease. Efforts to elucidate the role of CXCR7 have been limited by the lack of suitable chemical tools with a range of pharmacological profiles. A high-th...

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Bibliografski detalji
Izdano u:ACS Med Chem Lett
Glavni autori: Menhaji-Klotz, Elnaz, Ward, Jessica, Brown, Janice A., Loria, Paula M., Tan, Carina, Hesp, Kevin D., Riccardi, Keith A., Litchfield, John, Boehm, Markus
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2020
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7294705/
https://ncbi.nlm.nih.gov/pubmed/32551020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.0c00163
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