Roles of Membrane Domains in Integrin-Mediated Cell Adhesion

af Lietha, Daniel, Izard, Tina
Udgivet i Int J Mol Sci (2020)

Crystal Structures of the FAK Kinase in Complex with TAE226 and Related Bis-Anilino Pyrimidine Inhibitors Reveal a Helical DFG Conformation

af Lietha, Daniel, Eck, Michael J.
Udgivet 2008

FAK Structure and Regulation by Membrane Interactions and Force in Focal Adhesions

af Tapial Martínez, Paula, López Navajas, Pilar, Lietha, Daniel
Udgivet i Biomolecules (2020)

Tyrosine Phosphorylation of Rac1: A Role in Regulation of Cell Spreading

af Chang, Fumin, Lemmon, Christopher, Lietha, Daniel, Eck, Michael, Romer, Lewis
Udgivet 2011

New approaches for mapping the recognition sites in protein–GAG interactions: a study of GAG binding by hepatocyte growth factor/scatter factor

af Deakin, Jon A, Lietha, Daniel, Gherardi, Ermanno, Gallagher, John T, Lyon, Malcolm
Udgivet 2004

Allosteric Regulation of Focal Adhesion Kinase by PIP(2) and ATP

af Zhou, Jing, Bronowska, Agnieszka, Le Coq, Johanne, Lietha, Daniel, Gräter, Frauke
Udgivet i Biophys J (2015)

Crystal structures of NK1–heparin complexes reveal the basis for NK1 activity and enable engineering of potent agonists of the MET receptor

af Lietha, Daniel, Chirgadze, Dimitri Y., Mulloy, Barbara, Blundell, Tom L., Gherardi, Ermanno
Udgivet 2001

Structural basis for the autoinhibition of Focal Adhesion Kinase

af Lietha, Daniel, Cai, Xinming, Ceccarelli, Derek F.J., Li, Yiqun, Schaller, Michael D., Eck, Michael J.
Udgivet 2007

ORP2 couples LDL‐cholesterol transport to FAK activation by endosomal cholesterol/PI(4,5)P(2) exchange

af Takahashi, Kohta, Kanerva, Kristiina, Vanharanta, Lauri, Almeida‐Souza, Leonardo, Lietha, Daniel, Olkkonen, Vesa M, Ikonen, Elina
Udgivet i EMBO J (2021)

Alternative Activation Mechanisms of Protein Kinase B Trigger Distinct Downstream Signaling Responses

af Balzano, Deborah, Fawal, Mohamad-Ali, Velázquez, Jose V., Santiveri, Clara M., Yang, Joshua, Pastor, Joaquín, Campos-Olivas, Ramón, Djouder, Nabil, Lietha, Daniel
Udgivet i J Biol Chem (2015)

Structural basis for interdomain communication in SHIP2 providing high phosphatase activity

af Le Coq, Johanne, Camacho-Artacho, Marta, Velázquez, José Vicente, Santiveri, Clara M, Gallego, Luis Heredia, Campos-Olivas, Ramón, Dölker, Nicole, Lietha, Daniel
Udgivet i eLife (2017)

Spatial and Temporal Regulation of Focal Adhesion Kinase Activity in Living Cells

af Cai, Xinming, Lietha, Daniel, Ceccarelli, Derek F., Karginov, Andrei V., Rajfur, Zenon, Jacobson, Ken, Hahn, Klaus M., Eck, Michael J., Schaller, Michael D.
Udgivet 2008

A Synergistic Anti-Cancer FAK and HDAC Inhibitor Combination Discovered by a Novel Chemical-Genetic High-Content Phenotypic Screen

af Dawson, John C., Serrels, Bryan, Byron, Adam, Muir, Morwenna T., Makda, Ashraff, García-Muñoz, Amaya, von Kriegsheim, Alex, Lietha, Daniel, Carragher, Neil O., Frame, Margaret C.
Udgivet i Mol Cancer Ther (2020)

Structural and mechanistic insights into mechanoactivation of focal adhesion kinase

af Bauer, Magnus Sebastian, Baumann, Fabian, Daday, Csaba, Redondo, Pilar, Durner, Ellis, Jobst, Markus Andreas, Milles, Lukas Frederik, Mercadante, Davide, Pippig, Diana Angela, Gaub, Hermann Eduard, Gräter, Frauke, Lietha, Daniel
Udgivet i Proc Natl Acad Sci U S A (2019)

Phosphatidylinositol 4,5-bisphosphate triggers activation of focal adhesion kinase by inducing clustering and conformational changes

af Goñi, Guillermina M., Epifano, Carolina, Boskovic, Jasminka, Camacho-Artacho, Marta, Zhou, Jing, Bronowska, Agnieszka, Martín, M. Teresa, Eck, Michael J., Kremer, Leonor, Gräter, Frauke, Gervasio, Francesco Luigi, Perez-Moreno, Mirna, Lietha, Daniel
Udgivet 2014

Structural basis of Focal Adhesion Kinase activation on lipid membranes

af Acebrón, Iván, Righetto, Ricardo D, Schoenherr, Christina, de Buhr, Svenja, Redondo, Pilar, Culley, Jayne, Rodríguez, Carlos F, Daday, Csaba, Biyani, Nikhil, Llorca, Oscar, Byron, Adam, Chami, Mohamed, Gräter, Frauke, Boskovic, Jasminka, Frame, Margaret C, Stahlberg, Henning, Lietha, Daniel
Udgivet i EMBO J (2020)

A Conformation Selective Mode of Inhibiting SRC Improves Drug Efficacy and Tolerability

af Temps, Carolin, Lietha, Daniel, Webb, Emily R., Li, Xue-Feng, Dawson, John C., Muir, Morwenna, Macleod, Kenneth G., Valero, Teresa, Munro, Alison F., Contreras-Montoya, Rafael, Luque-Ortega, Juan R., Fraser, Craig, Beetham, Henry, Schoenherr, Christina, Lopalco, Maria, Arends, Mark J., Frame, Margaret C., Qian, Bin-Zhi, Brunton, Valerie G., Carragher, Neil O., Unciti-Broceta, Asier
Udgivet i Cancer Res (2021)