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Spatial and Temporal Regulation of Focal Adhesion Kinase Activity in Living Cells

Focal adhesion kinase (FAK) is an essential kinase that regulates developmental processes and functions in the pathology of human disease. An intramolecular autoinhibitory interaction between the FERM and catalytic domains is a major mechanism of regulation. Based upon structural studies, a fluoresc...

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Bibliografiske detaljer
Main Authors: Cai, Xinming, Lietha, Daniel, Ceccarelli, Derek F., Karginov, Andrei V., Rajfur, Zenon, Jacobson, Ken, Hahn, Klaus M., Eck, Michael J., Schaller, Michael D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223290/
https://ncbi.nlm.nih.gov/pubmed/17967873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01324-07
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