Protein crystallography and drug discovery: recollections of knowledge exchange between academia and industry

nork Blundell, Tom L.
Argitaratua izan da IUCrJ (2017)

Symmetry, stability, and dynamics of multidomain and multicomponent protein systems

nork Blundell, Tom L., Srinivasan, N.
Argitaratua 1996

Discarding Functional Residues from the Substitution Table Improves Predictions of Active Sites within Three-Dimensional Structures

nork Gong, Sungsam, Blundell, Tom L.
Argitaratua 2008

Ulla: a program for calculating environment-specific amino acid substitution tables

nork Lee, Semin, Blundell, Tom L.
Argitaratua 2009

Structural and Functional Restraints on the Occurrence of Single Amino Acid Variations in Human Proteins

nork Gong, Sungsam, Blundell, Tom L.
Argitaratua 2010

CODA: A combined algorithm for predicting the structurally variable regions of protein models

nork Deane, Charlotte M., Blundell, Tom L.
Argitaratua 2001

On the evolutionary conservation of hydrogen bonds made by buried polar amino acids: the hidden joists, braces and trusses of protein architecture

nork Worth, Catherine L, Blundell, Tom L
Argitaratua 2010

CREDO: a structural interactomics database for drug discovery

nork Schreyer, Adrian M., Blundell, Tom L.
Argitaratua 2013

XSuLT: a web server for structural annotation and representation of sequence-structure alignments

nork Ochoa-Montaño, Bernardo, Blundell, Tom L.
Argitaratua izan da Nucleic Acids Res (2017)

Prediction of impacts of mutations on protein structure and interactions: SDM, a statistical approach, and mCSM, using machine learning

nork Pandurangan, Arun Prasad, Blundell, Tom L.
Argitaratua izan da Protein Sci (2019)

An algorithm for predicting protein–protein interaction sites: Abnormally exposed amino acid residues and secondary structure elements

nork Hoskins, Jemima, Lovell, Simon, Blundell, Tom L.
Argitaratua 2006

BUB1 and BUBR1: multifaceted kinases of the cell cycle

nork Bolanos-Garcia, Victor M., Blundell, Tom L.
Argitaratua 2011

Structure of the Catalytic Region of DNA Ligase IV in Complex with an Artemis Fragment Sheds Light on Double-Strand Break Repair

nork Ochi, Takashi, Gu, Xiaolong, Blundell, Tom L.
Argitaratua 2013

The spatial organization of non-homologous end joining: From bridging to end joining

nork Ochi, Takashi, Wu, Qian, Blundell, Tom L.
Argitaratua 2014

Phosphopeptide interactions with BRCA1 BRCT domains: More than just a motif

nork Wu, Qian, Jubb, Harry, Blundell, Tom L.
Argitaratua izan da Prog Biophys Mol Biol (2015)

Model-building strategies for low-resolution X-ray crystallographic data

nork Karmali, Anjum M., Blundell, Tom L., Furnham, Nicholas
Argitaratua 2009

SDM—a server for predicting effects of mutations on protein stability and malfunction

nork Worth, Catherine L., Preissner, Robert, Blundell, Tom L.
Argitaratua 2011

TIMBAL v2: update of a database holding small molecules modulating protein–protein interactions

nork Higueruelo, Alicia P., Jubb, Harry, Blundell, Tom L.
Argitaratua 2013

Does a More Precise Chemical Description of Protein–Ligand Complexes Lead to More Accurate Prediction of Binding Affinity?

nork Ballester, Pedro J., Schreyer, Adrian, Blundell, Tom L.
Argitaratua 2014

The crystal structure of fibroblast growth factor 18 (FGF18)

nork Brown, Alan, Adam, Lucy E., Blundell, Tom L.
Argitaratua 2014