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BUB1 and BUBR1: multifaceted kinases of the cell cycle
The multidomain protein kinases BUB1 and BUBR1 (Mad3 in yeast, worms and plants) are central components of the mitotic checkpoint for spindle assembly (SAC). This evolutionarily conserved and essential self-monitoring system of the eukaryotic cell cycle ensures the high fidelity of chromosome segreg...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier Trends Journals
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3061984/ https://ncbi.nlm.nih.gov/pubmed/20888775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2010.08.004 |
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