Defining the Molecular Basis of BubR1 Kinetochore Interactions and APC/C-CDC20 Inhibition

BubR1 is essential for the mitotic checkpoint that prevents aneuploidy in cellular progeny by triggering anaphase delay in response to kinetochores incorrectly/not attached to the mitotic spindle. Here, we define the molecular architecture of the functionally significant N-terminal region of human B...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: D'Arcy, Sheena, Davies, Owen R., Blundell, Tom L., Bolanos-Garcia, Victor M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863239/
https://ncbi.nlm.nih.gov/pubmed/20220147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.082016
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker