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Defining the Molecular Basis of BubR1 Kinetochore Interactions and APC/C-CDC20 Inhibition
BubR1 is essential for the mitotic checkpoint that prevents aneuploidy in cellular progeny by triggering anaphase delay in response to kinetochores incorrectly/not attached to the mitotic spindle. Here, we define the molecular architecture of the functionally significant N-terminal region of human B...
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| Huvudupphovsmän: | , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Biochemistry and Molecular Biology
2010
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2863239/ https://ncbi.nlm.nih.gov/pubmed/20220147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.082016 |
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