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Transcriptional Control of BubR1 by p53 and Suppression of Centrosome Amplification by BubR1
Elimination of the regulatory mechanism underlying numeral homeostasis of centrosomes, as seen in cells lacking p53, results in abnormal amplification of centrosomes, which increases the frequency of chromosome segregation errors, and thus contributes to the chromosome instability frequently observe...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1087701/ https://ncbi.nlm.nih.gov/pubmed/15870277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.10.4046-4061.2005 |
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