CENP-A Is Required for Accurate Chromosome Segregation and Sustained Kinetochore Association of BubR1

CENP-A is an evolutionarily conserved, centromere-specific variant of histone H3 that is thought to play a central role in directing kinetochore assembly and in centromere function. Here, we have analyzed the consequences of disrupting the CENP-A gene in the chicken DT40 cell line. In CENP-A-deplete...

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Detalhes bibliográficos
Main Authors: Régnier, Vinciane, Vagnarelli, Paola, Fukagawa, Tatsuo, Zerjal, Tatiana, Burns, Elizabeth, Trouche, Didier, Earnshaw, William, Brown, William
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Chromosome Structure and Dynamics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087704/
https://ncbi.nlm.nih.gov/pubmed/15870271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.10.3967-3981.2005
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